COMPOSITION
Each sachet contains :
Isometamidium Chloride Hydrochloride 1 g
INDICATIONS
ISOMID is indicated for treatment and prevention of trypanosomiasis caused by Trypanosoma spp. in Cattle, Goats, Sheep, Camels, Horses and Dogs. A preventive dosage ensures protection for 2 to 4 months. When clinical cases occur, the whole group should be treated.
CONTRA-INDICATIONS
- ISOMID should not be administered subcutaneously.
- Avoid concurrent administration of other trypanocidal drugs, particularly diminazene aceturate.
- Avoid underdosing.
DIRECTIONS
Dissolve 1 g of powder with 50 ml (2% solution) or 100 ml (1% solution) of sterile water.
DOSE RATE, PRECAUTIONS
For use in cattle, sheep, goats, camel, horses & buffaloes.
DOSAGE AND ADMINISTRATION
For parenteral administration.
Dissolve the content of one sachet of ISOMID (1 g) in 50 ml or 100 ml of sterile water for injection to obtain a 2% (20 mg/ml) or a 1% (10 mg/ml) solution, respectively.
Repeated injections are needed at intervals of 10 to 12 weeks or more, depending on the level of fly challenge.
Calves, Goats and Sheep : treatment : 0.25 - 0.5 mg/kg by deep IM injection.
prevention : 0.5 - 1 mg/kg by deep IM injection.
Camels : 0.5 - 0.75 mg/kg using a 1% solution by very slow IV injection.
Horses : 0.5 mg/kg by deep IM injection.
Dogs : 1 mg/kg by deep IM injection.
Deep IM injection should occur preferably in the middle third of the neck in large animals. Doses exceeding 10 ml should be injected at multiple injection sites on each side of the neck. Make sure that the syringe is completely empty before retracting it from the IM injection site. Afterwards, to prevent leakage of ISOMID into subcutaneous tissues, firm pressure must be applied on the injection site. Sheep and Goats are injected deep in their thigh muscles.